{"id":14523,"date":"2023-01-16T11:51:49","date_gmt":"2023-01-16T10:51:49","guid":{"rendered":"https:\/\/beatapawlikowska.com\/?p=14523"},"modified":"2023-01-16T11:51:49","modified_gmt":"2023-01-16T10:51:49","slug":"depresja-najnowsze-badania-naukowe","status":"publish","type":"post","link":"https:\/\/beatapawlikowska.norbibednar.dev\/?p=14523","title":{"rendered":"Depresja. Najnowsze badania naukowe"},"content":{"rendered":"\n<p>Najnowsze badania wskazuj\u0105 na to, \u017ce:<\/p>\n\n\n\n<p>\u2022 Leki przeciwdepresyjne to substancje psychoaktywne, kt\u00f3re zmieniaj\u0105 dzia\u0142anie m\u00f3zgu. \u2022 Nie wiadomo jaka jest przyczyna depresji (ani schizofrenii ani innych chor\u00f3b umys\u0142owych).<\/p>\n\n\n\n<p>\u2022 Leki przeciwdepresyjne nie \u201enaprawiaj\u0105 braku r\u00f3wnowagi chemicznej\u201d w m\u00f3zgu, a raczej powoduj\u0105 zmiany w m\u00f3zgu, kt\u00f3re maj\u0105 wp\u0142yw na emocje, osobowo\u015b\u0107 i funkcjonowanie ca\u0142ego organizmu.<\/p>\n\n\n\n<p>\u2022 Leki przeciwdepresyjne mog\u0105 wywo\u0142a\u0107 d\u0142ugotrwa\u0142e objawy odstawienia (73,5% os\u00f3b), dysfunkcje seksualne (71,8%), przyrost masy cia\u0142a (65,3%), zoboj\u0119tnienie emocjonalne (64,5%) i uzale\u017cnienie (43%).<\/p>\n\n\n\n<p>\u2022 U niekt\u00f3rych os\u00f3b d\u0142ugotrwa\u0142e stosowanie lek\u00f3w przeciwdepresyjnych mo\u017ce zwi\u0119ksza\u0107 depresj\u0119 i wywo\u0142a\u0107 chroniczny stan depresji.<\/p>\n\n\n\n<p>Dlaczego ja o tym m\u00f3wi\u0119? Jako dziennikarz z bieg\u0142\u0105 znajomo\u015bci\u0105 angielskiego mam dost\u0119p do najnowszych bada\u0144 naukowych. Przekazuj\u0119 Wam wiedz\u0119, kt\u00f3ra w przypadku wielu os\u00f3b mo\u017ce si\u0119 okaza\u0107 przydatna. Nie jestem lekarzem, nie zalecam niczego. Zadaniem dziennikarza jest przekazywanie informacji, kt\u00f3re mog\u0105 by\u0107 niedost\u0119pne opinii publicznej i mog\u0105 nawet narusza\u0107 istniej\u0105cy spos\u00f3b my\u015blenia\/post\u0119powania w danej sprawie. Przedstawiam fakty. Sami zdecydujecie co z tymi faktami zrobi\u0107.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"Depresja. Najnowsze badania naukowe\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/H1DYxF5zIMg?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>Badania wspomniane w filmie:<\/p>\n\n\n\n<p>1. Moncrieff, J., Cooper, R.E., Stockmann, T. et al. The serotonin theory of depression: a systematic umbrella review of the evidence. Molecular Psychiatry, 2022.<\/p>\n\n\n\n<p>2. Charles B. Nemeroff, The State of Our Understanding of the Pathophysiology and Optimal Treatment of Depression: Glass Half Full or Half Empty? American Journal of Psychiatry, 2020.<\/p>\n\n\n\n<p>3. Moncrieff J. Antidepressants: misnamed and misrepresented. World Psychiatry, 2015.<\/p>\n\n\n\n<p>4. Moncrieff J, Cohen D, Porter S., The psychoactive effects of psychiatric medication: the elephant in the room. Journal of Psychoactive Drugs, 2013.<\/p>\n\n\n\n<p>5. Moncrieff J, Cohen D,. Do antidepressants cure or create abnormal brain states? PLoS Medicine, 2006.<\/p>\n\n\n\n<p>6. Cartwright C, Gibson K, Read J, Cowan O, Dehar T., Long-term antidepressant use: patient perspectives of benefits and adverse effects. Patient Preference and Adherence, 2016.<\/p>\n\n\n\n<p>7. Albert PR, Benkelfat C., The neurobiology of depression&#8211;revisiting the serotonin hypothesis. II. Genetic, epigenetic and clinical studies. Philosophical Transactions of the Royal Society of London, Biological Sciences, 2013.<\/p>\n\n\n\n<p>8. Cowen PJ, Browning M., What has serotonin to do with depression? World Psychiatry, 2015.<\/p>\n\n\n\n<p>9. El-Mallakh RS, Gao Y, Jeannie Roberts R., Tardive dysphoria: the role of long term antidepressant use in-inducing chronic depression. Medical Hypotheses, 2011.<\/p>\n\n\n\n<p>10. Moncrieff J, Cohen D, Do Antidepressants Cure or Create Abnormal Brain States? PLoS Medicine, 2006<\/p>\n\n\n\n<p>11. Ma H, Cai M, Wang H. Emotional Blunting in Patients With Major Depressive Disorder: A Brief Non-systematic Review of Current Research. Frontiers in Psychiatry, 2021.<\/p>\n\n\n\n<p>12. R\u00fctgen M, Pletti C, Tik M, Kraus C, Pfabigan DM, Sladky R, Kl\u00f6bl M, Woletz M, Vanicek T, Windischberger C, Lanzenberger R, Lamm C., Antidepressant treatment, not depression, leads to reductions in behavioral and neural responses to pain empathy. Translational Psychiatry, 2019.<\/p>\n\n\n\n<p>13. R\u00fctgen M, Pfabigan DM, Tik M, Kraus C, Pletti C, Sladky R, Kl\u00f6bl M, Woletz M, Vanicek T, Windischberger C, Lanzenberger R, Lamm C., Detached empathic experience of others&#8217; pain in remitted states of depression &#8211; An fMRI study. Neuroimage Clinical, 2021.<\/p>\n\n\n\n<p>14. Davies J, Read J., A systematic review into the incidence, severity and duration of antidepressant withdrawal effects: Are guidelines evidence-based? Addictive Behaviors, 2019.<\/p>\n\n\n\n<p>15. Shadrina M, Bondarenko EA, Slominsky PA., Genetics Factors in Major Depression Disease. Frontiers in Psychiatry, 2018.<\/p>\n\n\n\n<p>16. Fava GA. May antidepressant drugs worsen the conditions they are supposed to treat? The clinical foundations of the oppositional model of tolerance. Therapeutic Advances in Psychopharmacology, 2020.<\/p>\n\n\n\n<p>17. Edinoff AN, Nix CA, Hollier J, Sagrera CE, Delacroix BM, Abubakar T, Cornett EM, Kaye AM, Kaye AD., Benzodiazepines: Uses, Dangers, and Clinical Considerations. Neurology International, 2021.<\/p>\n\n\n\n<p>18. Benjamin Ang, Mark Horowitz, Joanna Moncrieff, Is the chemical imbalance an \u2018urban legend\u2019? An exploration of the status of the serotonin theory of depression in the scientific literature. SSM &#8211; Mental Health, 2022.<\/p>\n\n\n\n<p>19. Penckofer S, Kouba J, Byrn M, Estwing Ferrans C. Vitamin D and depression: where is all the sunshine? Issues in Mental Health Nursing, 2010.<\/p>\n\n\n\n<p>20. Craft LL, Perna FM., The Benefits of Exercise for the Clinically Depressed. Primary Care Companion to the Journal of Clinical Psychiatry, 2004.<\/p>\n\n\n\n<p>21. Gautam M, Tripathi A, Deshmukh D, Gaur M., Cognitive Behavioral Therapy for Depression. Indian Journal of Psychiatry, 2020.<\/p>\n\n\n\n<p>22. Mark Abie Horowitz, David Taylor, Distinguishing relapse from antidepressant withdrawal: clinical practice and antidepressant discontinuation studies. Cambridge University Press, 2022.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Najnowsze badania wskazuj\u0105 na to, \u017ce: \u2022 Leki przeciwdepresyjne to substancje psychoaktywne, kt\u00f3re zmieniaj\u0105 dzia\u0142anie m\u00f3zgu. \u2022 Nie wiadomo jaka<\/p>\n","protected":false},"author":2,"featured_media":14524,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-14523","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-filmy"],"_links":{"self":[{"href":"https:\/\/beatapawlikowska.norbibednar.dev\/index.php?rest_route=\/wp\/v2\/posts\/14523","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/beatapawlikowska.norbibednar.dev\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/beatapawlikowska.norbibednar.dev\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/beatapawlikowska.norbibednar.dev\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/beatapawlikowska.norbibednar.dev\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=14523"}],"version-history":[{"count":0,"href":"https:\/\/beatapawlikowska.norbibednar.dev\/index.php?rest_route=\/wp\/v2\/posts\/14523\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/beatapawlikowska.norbibednar.dev\/index.php?rest_route=\/wp\/v2\/media\/14524"}],"wp:attachment":[{"href":"https:\/\/beatapawlikowska.norbibednar.dev\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=14523"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/beatapawlikowska.norbibednar.dev\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=14523"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/beatapawlikowska.norbibednar.dev\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=14523"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}